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庞小燕

副教授

  • 电话:+86-021-34204878
  • 邮箱:xypang@sjtu.edu.cn

学术经历

  • 1999年毕业于兰州大学生物系,获细胞生物学专业应用微生物学方向硕士学位;2005年于ebet获生物化学与分子生物学专业微生物分子生态学方向博士学位。1999年至今在ebet工作,是微生物分子生态与生态基因组学实验室的骨干教师,承担相关科研工作和国家级精品课程“分子生物学”的部分教学工作。

研究方向

人和动物的肠道微生物组研究

主要为人和动物的肠道微生物组研究。目前主要致力于肠道菌群参与肥胖、糖尿病、大肠癌等疾病的发生、发展的机理研究以及肠道重要功能细菌的分子生物学特性研究。

代表论著

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    Zhang, C., Zhao, Y., Zhang, M., Pang, X., Wang, L., Zhao L., Structural resilience of the gut microbiota in adult mice under high fat dietary perturbations. ISME J. 2012, Accepted 

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    Wang T., Cai G., Qiu Y., Fei N., Zhang M., Pang X., Jia W., Cai S., Zhao L., Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers. ISME J. 2012, 6: 320-329 

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    Zhang C., Zhang M. Wang S., Han R., Cao Y., Hua W., Mao Y., Zhang X., Pang X., Wei C., Zhao G., Chen Y., Zhao L.. Interactions between gut microbiota, host genetics, and diet relevant to development of metabolic syndromes in mice. ISME J., 2010, 4: 232-241 

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    Shen J., Zhang B. Wei H., Che C., Ding D., Hua X., Bucheli P., Wang L., Li Y., Pang X.(通讯作者), Zhao L., Assessment of the modulating effects of fructo-oligosaccharides on fecal microbiota using human flora associated piglets. Arch. Microbio., 2010, 192: 959-968 

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    Wei H., Dong L., Wang T., Zhang M., Hua W., Zhang C., Pang X., Chen M., Su M., Qiu Y., Zhou M., Yang S., Chen Z., Rantalainen M., Nicholson J.K., Jia W., Wu D., Zhao L. Structural shifts of gutmicrobiota as surrogate endpoints for monitoring host health changes induced by carcinogen exposure, FEMS Microbiol. Ecol., 2010, 73: 577–586 

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    Zhang M., Zhang M., Zhang C., Du H., Wei G., Pang X., Zhou H., Liu B., Zhao L., Pattern extraction of structural responses of gut microbiota to rotavirus infection via multivariate statistical analysis of clone library data. FEMS Microbiol. Ecol., 2009, 70(2):21-29 

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    Li M., Zhou H., Hua W., Wang B., Wang S., Zhao G., Li L., Zhao L., Pang X.(通讯作者), Molecular diversity of Bacteroides spp. in human fecal microbiota as determined by group-specific 16S rRNA gene clone library analysis. Syst. Appl. Microbiol., 2009, 32: 193-200 

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    Li M., Wang B., Zhang M., Rantalainen M., Wang S., Zhou H., Zhang Y., Shen J., Pang X., Zhang M., Wei H., Chen Y., Lu H., Zuo J., Su M., Qiu Y., Jia W., Xiao C., Smith L.M., Yang S., Holmes E., Tang H., Zhao G., Nicholson J.K., Li L., Zhao L., Symbiotic gut microbes modulate human metabolic phenotypes. Proc. Natl. Acad. Sci. USA, 2008, 105: 2117-2122 

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    Wei H., Shen J., Pang X., Ding D., Zhang Y., Zhang B., Lua H., Wang T., Zhang C., Hua X., Li Cui, Zhao L., Fatal infection in human flora-associated piglets caused by the opportunistic pathogen Klebsiella pneumoniae from an apparently healthy human donor. J. Vet. Med. Sci., 2008, 70(7): 715–717 

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    Pang X., Hua X, Yang Q, Ding D, Che C, Cui L, Jia W, Bucheli P, Zhao L. Inter- species transplantation of gut microbiota from human to pigs. ISME Journal., 2007, 1:156–162